Parecoxib (Sodium)
Synonyms:3-(10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-YLIDENE)-N, N-DIMETHYL-1-PROPANAMINEHYDROCHLORIDE; AMITRIPTYLINEHYDROCHLORIDE98+%; AMITRIPTYLINEHYDROCHLORIDESOLUTION; 3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLIDENE)-N, N-DIMETHYL-1-PROPANAMINEHYDROCHLORIDE
CAS Nr.:198470-84-7 / 198470-85-8
Molecular Formula: C20H24ClN
Molecular Luj:313.86 ib
EINECS No.:208-964-6
Qauv
Daim ntawv thov:Pharmaceuticals, intermediates, APIs, kev cai synthesis, tshuaj
Superiority:Tus neeg muag khoom zoo tshaj plaws, siab zoo, tus nqi sib tw, xa khoom sai, teb sai
Kev siv:Antidepressant, muaj feem xyuam rau ntau yam kev nyuaj siab cov tsos mob ntawm kev nyuaj siab thiab organic psychosis
Yam muaj feem:BiogenicAmineTransportInhibitors; BiogenicAmineTransportInhibitorsObesityResearch; Neurotransmission; Neurotransmission (Obesity); Neurotransmitters; Adrenoceptor; Amines; Intermediates & FineChemicals; Pharmaceuticals
Melting point | 196-197 ° C |
Flash point | 11 ° C |
Qhov ntom | 1.3134 (kev kwv yees kwv yees) |
Refractive Index | 1.5490 (kwv yees) |
Solubility | H2O; soluble |
Daim ntawv | hmoov |
pKa | 9.4 (ntawm 25 ℃) |
PH | 4.5 ~ 6.0 (10g / l, 25 ℃) |
Xim | dawb mus dawb |
Dej solubility | Yuav luag pob tshab |
Hazard Category Code | 23/24/25-36/37/38-42/43-63-39/23/24/25-11-50/53-36-22 NWS |
Cov lus hais txog kev nyab xeeb | 22-26-36/37/39-45-36/37-16-61-60-7 hnub |
Dangerous khoom thauj No | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | ib 945000 |
Hazard theem | 6.1 (b) |
Ntim qeb | III |
HS Code | 29214990 ib |
Tshwj xeeb specifications raws li tus neeg yuav tsum tau muaj | |
Qhov tshwm sim | Dawb crystalline los yog dawb, yuav luag dawb hmoov |
Poob rau ziab | 0.5% max |
Melting point | 195-199 ℃ |
Residue ntawm ignition | 0.1% max |
Purity (HPLC) | 98.0% -102.0% (raws li kev ziab) |
Cov qauv zoo | USP36 Ib |
Kev ceev faj rau kev nyab xeeb:
Tuav nyob rau hauv qhov chaw zoo ventilated. Hnav khaub ncaws tiv thaiv zoo. Tsis txhob kov ntawm daim tawv nqaij thiab qhov muag. Tsis txhob tsim cov hmoov av thiab aerosols. Siv cov cuab yeej tsis muaj teeb meem. Tiv thaiv hluav taws los ntawm electrostatic tawm chav.
Cov xwm txheej rau kev ruaj ntseg cia, suav nrog txhua qhov tsis sib xws:
Khaws lub thawv kaw kom nruj rau hauv qhov chaw qhuav thiab qhov cua zoo. Pom zoo cia kub: 2 - 8 deg C. Khaws rau hauv qhov chaw qhuav. Amitriptyline hydrochloride.
Jingye muaj 86 pawg ntawm cov reactors nyob rau hauv tag nrho, uas lub ntim ntawm enamel reactor yog 69, los ntawm 50 mus rau 3000L. Tus naj npawb ntawm stainless reactors yog 18, los ntawm 50 mus rau 3000L. QC tau nruab nrog ntau pua ntawm txhua yam kev ntsuas ntsuas. Nws tuaj yeem ua tau raws li kev lag luam ntau lawm thiab kev tsom xam ntawm cov khoom. Cov khoom no yog cov khoom lag luam zoo tshaj plaws thiab tuaj yeem xa tuaj raws li cov neeg siv khoom xav tau.
Jingye Pharmaceutical tswj thiab kev ua haujlwm tsim khoom nruj me ntsis raws li GMP cov cai, uas pab Jingye Pharmaceutical xa tawm nws cov khoom mus rau Tebchaws Europe, Amelikas thiab South thiab East Asia. Nrog rau cov chaw tsim khoom niaj hnub, cov cuab yeej tshuaj ntsuam xyuas qib siab thiab lub suab EHS, Jingye Pharmaceutical tau ntawv pov thawj los ntawm ISO9001, ISO14001 thiab GB / T28001, thiab tam sim no nws yog nyob rau hauv tus txheej txheem rau tus kws tshaj lij GMP Pharmaceuticals Chaw Tsim Tshuaj.